Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Rapid fluid replacement: a new methodology.

K V Iserson, A K Reeter

    Annals of Emergency Medicine
    |February 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Rapid fluid resuscitation is critical for trauma survival. This study introduces a novel large-bore catheter system significantly increasing fluid infusion rates, enhancing patient survivability in critical care scenarios.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Color blindness and health care personnel.

    Archives of internal medicine·2001
    Same author

    Emergency physicians and physician-assisted suicide, Part I: a review of the physician-assisted suicide debate.

    Annals of emergency medicine·2001
    Same author

    Emergency physicians and physician-assisted suicide, Part II: emergency care for patients who have attempted physician-assisted suicide.

    Annals of emergency medicine·2001
    Same author

    Terrorism and the ethics of emergency medical care.

    Annals of emergency medicine·2001
    Same author

    Jehovah's Witnesses and medical practice in Mexico: religious freedom, parens patriae, and the right to life.

    Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees·2001
    Same author

    Wilderness mortalities: a 13-year experience.

    Annals of emergency medicine·2001

    Area of Science:

    • Medical Devices
    • Trauma Care
    • Fluid Resuscitation

    Background:

    • Rapid fluid replacement is a critical determinant of survival in trauma patients.
    • Current percutaneous fluid infusion systems have limitations in flow rate.

    Purpose of the Study:

    • To describe and evaluate a novel fluid infusion system designed to increase fluid flow rates for trauma patients.
    • To assess the efficacy and safety of a large-bore catheter system for rapid fluid administration.

    Main Methods:

    • Development of a fluid infusion system utilizing a 14 French (4.5-mm internal diameter) central venous catheter inserted via the Seldinger technique.
    • A manifold design allowing simultaneous infusion from multiple IV bags through a single line.
    • In vitro and in vivo (canine model) testing to measure fluid flow rates (normal saline and packed red blood cells) under gravity and pressurized conditions.

    Related Experiment Videos

    Main Results:

    • In vitro testing demonstrated gravity flow rates exceeding 850 mL/min (normal saline) and pressurized flow rates over 2.0 L/min.
    • Under pressure, packed red blood cells (42% hematocrit) flowed at 1,725 mL/min.
    • In vivo canine studies showed maximum gravity flow rates of ~650 mL/min and pressurized flow rates exceeding 1,600 mL/min.
    • No significant adverse events related to large-bore catheterization were observed.

    Conclusions:

    • The described fluid infusion system offers a substantial fourfold increase in flow rates compared to existing percutaneous methods.
    • This novel system has the potential to improve fluid resuscitation efficiency in critically injured patients.
    • The system demonstrated safe and effective rapid fluid and blood product administration in preclinical testing.