Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A new approach to absorptive function of gallbladder.

H Igimi, F Yamamoto, Y Ikejiri

    Gastroenterologia Japonica
    |January 1, 1978
    PubMed
    Summary

    The gallbladder concentrates bile by transporting electrolytes like sodium and chloride against water flow. This process alters hepatic bile composition, approaching gallbladder bile levels, but is affected by cholecystitis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Very high resolution single pass HLA genotyping using amplicon sequencing on the 454 next generation DNA sequencers: Comparison with Sanger sequencing.

    Human immunology·2015
    Same author

    Altered expression of dermokine in skin disorders.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2012
    Same author

    Amending reduced fish-meal feeds with marine lecithin, but not soy lecithin, improves the growth of juvenile cobia and may attenuate heightened responses to stress challenge.

    Journal of animal physiology and animal nutrition·2011
    Same author

    Blood cardioplegia serves as a bicarbonate donor to the myocardium during ischemia: effects of anoxia and hypercapnia on acid-base characteristics of blood cardioplegic solution.

    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes·2011
    Same author

    [Management of mediastinitis and preventions of perioperative nosocomial infection after cardiovascular surgery].

    Kyobu geka. The Japanese journal of thoracic surgery·2010
    Same author

    [Surgical repair of extracardiac unruptured aneurysm of the sinus of Valsalva].

    Kyobu geka. The Japanese journal of thoracic surgery·2008

    Area of Science:

    • Gastroenterology
    • Physiology
    • Biliary System Research

    Background:

    • Bile concentration is crucial for digestion and nutrient absorption.
    • Understanding gallbladder function is key to biliary system health.

    Purpose of the Study:

    • To elucidate the mechanism of bile concentration in the canine gallbladder.
    • To investigate electrolyte and water transport across the gallbladder epithelium.

    Main Methods:

    • Normal canine gallbladders were cannulated via the cystic duct.
    • Hypotonic, isotonic, and hypertonic salines, plus hepatic and gallbladder biles, were introduced.
    • Electrolyte and volume changes were monitored.

    Main Results:

    • Low molecular electrolytes (Na+, Cl-) were transported against water flux.
    • Hepatic bile volume decreased significantly, with electrolyte levels approaching gallbladder bile.
    • Chemically induced cholecystitis altered bile concentration results.

    Conclusions:

    • The gallbladder epithelium actively transports electrolytes, driving water movement for bile concentration.
    • Hepatic bile undergoes significant modification within the gallbladder.
    • Gallbladder inflammation impacts normal bile concentration mechanisms.

    Related Experiment Videos