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Related Experiment Videos

Tonic pupil with giant cell arteritis.

J Currie, S Lessell

    The British Journal of Ophthalmology
    |February 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Giant cell arteritis can cause vision loss and rarely, bilateral tonic pupils due to ciliary ganglion ischemia. Anatomical factors may protect these specific arteries, or the condition may be underdiagnosed.

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    Area of Science:

    • Ophthalmology
    • Neurology
    • Rheumatology

    Background:

    • Giant cell arteritis (GCA) is a systemic vasculitis often affecting cranial arteries.
    • GCA commonly leads to ischemic optic neuropathy and other ocular complications due to vascular occlusion.
    • Pupillary abnormalities are less frequently reported in GCA patients.

    Observation:

    • A patient diagnosed with giant cell arteritis and ischemic optic neuropathy presented with bilateral tonic pupils.
    • Tonic pupils are characterized by a slow, sustained constriction in response to light and near stimuli.
    • This pupillary finding suggests potential ischemia affecting the ciliary ganglia.

    Findings:

    • The development of tonic pupils in this GCA patient indicates a possible, though rare, neurological complication.

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  • Ischemia of the ciliary ganglia, supplied by arteries implicated in GCA, is a proposed mechanism.
  • The rarity of tonic pupils in GCA may be due to protective anastomotic patterns in the blood supply to the ciliary ganglia.

    • Implications:

    • Highlights the potential for ciliary ganglion ischemia in GCA, leading to pupillary abnormalities.
    • Suggests that tonic pupils might be an underrecognized manifestation of GCA.
    • Emphasizes the importance of considering pupillary function in the comprehensive ophthalmic evaluation of GCA patients.