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Abstract:
This study is a qualitative and quantitative comparative analysis of the phosphoglycerides found in human brain tumors and normal brain tissue. Astrocytomas, glioblastomas, meningosarcomas and ependymomas were studied and, in all of these, the total phosphoglyceride levels were found to be significantly lower than in normal controls. Fractionation of the phosphoglycerides by thin-layer chromatography showed definite qualitative and/or quantitative differences in the phosphoglyceride fractions of tumor tissues in comparison with normal brain tissue.