Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ollier's disease with multiple sarcomatous transformations.

S B Goodman, R S Bell, V L Fornasier

    Human Pathology
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Canadian Surgery Forum: Abstracts of presentations to the Annual Meetings of the Canadian Association of Bariatric Physicians and Surgeons, Canadian Association of General Surgeons, Canadian Association of Thoracic Surgeons, Canadian Hepato-Pancreato-Biliary Association, Canadian Society of Surgical Oncology, Canadian Society of Colon and Rectal Surgeons, Vancouver, BC, Sept. 17-21, 2013.

    Canadian journal of surgery. Journal canadien de chirurgie·2025
    Same author

    Hip or spine surgery first?: a survey of treatment order for patients with concurrent degenerative hip and spinal disorders

    The bone & joint journal·2019
    Same author

    Cytotoxicity of drugs injected into joints in orthopaedics.

    Bone & joint research·2019
    Same author

    Metal-on-metal total hip arthroplasty is not associated with cardiac disease.

    The bone & joint journal·2018
    Same author

    An evidence-based guide to the treatment of osteonecrosis of the femoral head.

    The bone & joint journal·2017
    Same author

    The vestibulocochlear bases for wartime posttraumatic stress disorder manifestations.

    Medical hypotheses·2017
    Same journal

    TRPS1 and GATA3 Expression in BRG1/SMARCA4-deficient Malignant Neoplasms.

    Human pathology·2026
    Same journal

    Clinicopathologic and Molecular Characteristics of Acral Melanomas Harboring RARA Fusions.

    Human pathology·2026
    Same journal

    Clinical Impact of Second Opinion Consultation in Bladder Biopsies and Transurethral Resection of Bladder Tumors.

    Human pathology·2026
    Same journal

    Prognostic relevance and molecular correlates of Claudin-1 expression in pancreatic neuroendocrine tumors.

    Human pathology·2026
    Same journal

    Mixed Phenotype Acute Leukemia: Lineage Assignment, Immunophenotypic Classification and Genetic Insights.

    Human pathology·2026
    Same journal

    Chronic myelomonocytic leukemia revisited: A comprehensive review with emphasis on the oligomonocytic subtype.

    Human pathology·2026
    See all related articles

    Monomelic Ollier's disease can present with multiple chondrosarcomas. This case highlights unusual widespread malignant transformation in a patient's leg bones.

    Area of Science:

    • Orthopedic Oncology
    • Skeletal Dysplasias
    • Pathology

    Background:

    • Ollier's disease, a rare skeletal dysplasia, is characterized by multiple enchondromas.
    • The monomelic form affects a single limb, leading to deformity.
    • Malignant transformation, typically to chondrosarcoma, is a known complication.

    Observation:

    • A 53-year-old male presented with pain and thigh enlargement due to the monomelic form of Ollier's disease affecting his left leg.
    • Imaging and biopsy confirmed chondrosarcomatous transformation in the distal left femur.
    • Surgical hip disarticulation was performed for treatment.

    Findings:

    • The surgical specimen revealed multiple foci of chondrosarcoma at various developmental stages.
    • These malignant transformations were distributed throughout the left femur, tibia, and fibula.

    Related Experiment Videos

  • This represents an unusual presentation of widespread, multifocal sarcomatous change in Ollier's disease.

    • Implications:

    • This case underscores the importance of vigilant monitoring for malignant transformation in Ollier's disease, even in its monomelic form.
    • The multifocal nature of the chondrosarcoma suggests a potential for diffuse neoplastic progression within affected skeletal segments.
    • Further research into the pathogenesis of widespread malignant transformation in Ollier's disease may inform future treatment strategies.