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Related Experiment Videos

Formed visual hallucinations after metrizamide myelography.

D M Bachman

    American Journal of Ophthalmology
    |January 1, 1984
    PubMed
    Summary

    A 77-year-old woman experienced visual hallucinations after metrizamide myelography. These symptoms resolved as inflammatory markers decreased, suggesting a link to the contrast agent.

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    Area of Science:

    • Neurology
    • Radiology
    • Ophthalmology

    Background:

    • Metrizamide myelography is an imaging technique used to diagnose spinal cord and central nervous system conditions.
    • Downbeat nystagmus is an involuntary rhythmic eye movement that can be caused by various neurological disorders.

    Observation:

    • A 77-year-old woman developed visual hallucinations, including geometric shapes and human figures, 12 hours post-metrizamide myelography of the posterior fossa.
    • She presented with an elevated white blood cell count (26,000/mm3) and elevated serum creatine phosphokinase (438 units/liter).

    Findings:

    • Hallucinations resolved within two days.
    • White blood cell count decreased to 17,000/mm3 and serum creatine phosphokinase to 105 units/liter.
    • The patient's symptoms likely resulted from metrizamide penetration into the temporal lobe and visual association cortex.

    Implications:

    • This case highlights a potential neurological side effect of metrizamide, specifically visual disturbances.
    • Early identification and monitoring of inflammatory markers may be crucial in managing patients undergoing metrizamide myelography.
    • Further research is needed to understand the neurotoxic effects of metrizamide and optimize patient safety.

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