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Exercise testing to evaluate patients with pulmonary vascular disease.
The American Review of Respiratory Disease
|February 1, 1984
Summary
Maximal oxygen uptake (VO2 max) can be measured noninvasively in pulmonary vascular disease patients. This measurement shows potential for screening and predicting disease severity by assessing oxygen utilization and cardiac output.
Area of Science:
- Cardiopulmonary Exercise Testing
- Pulmonary Vascular Disease Diagnostics
Background:
- Pulmonary vascular disease diagnosis often requires invasive hemodynamic monitoring.
- Noninvasive methods for assessing disease severity are needed.
Purpose of the Study:
- To evaluate the utility of noninvasive gas exchange measurements for assessing pulmonary vascular disease.
- To determine if maximal oxygen uptake (VO2 max) can predict hemodynamic profiles.
Main Methods:
- Progressive exercise testing with noninvasive gas exchange measurements.
- Analysis of maximal oxygen uptake (VO2 max) and anaerobic threshold.
Main Results:
- Maximal oxygen uptake (VO2 max) is determinable noninvasively in these patients.
- VO2 max correlates with cardiac output and inversely with pulmonary vascular resistance and arterial pressure.
Conclusions:
- Noninvasive VO2 max determination is a practical screening technique for pulmonary vascular disease.
- This method has potential for predicting disease severity and hemodynamic status.