Related Experiment Video
Updated: Jul 24, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
Published on: November 21, 2013
Childhood schizophrenia 20 years later
Abstract:
We followed up 20 patients diagnosed as childhood schizophrenics more than 20 years earlier. The aims were to find out what patients were like as children, to see whether they had changed as adults, and to determine whether, as adults, they differed from schizophrenics whose conditions were not diagnosed in childhood. The original diagnosis was made by one child psychiatrist. All patients' conditions were rediagnosed retrospectively by strict application of the British Working Party's "nine diagnostic points." All adult patients were personally examined by one or both of us. We found that, apart from becoming generally quieter, patients were almost unchanged and retained most of the cardinal symptoms of childhood schizophrenia. They proved to be similar to adult simple schizophrenics. Whether or not patients were termed schizophrenic as adults depended on the criteria used for diagnosis. Age at onset did not affect outcome, with the exception of more reported hallucinatory experiences in the late-onset group.
Related Concept Videos
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...
Schizophrenia
Negative and Cognitive Symptoms of Schizophrenia
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Biological Causes of Schizophrenia
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin studies.
Psychological and Sociocultural Causes of Schizophrenia
Positive Symptoms of Schizophrenia: Hallucinations and Delusions
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes loosely...

