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Oxyphil cell adenomas. Three case reports.

K A Lamping, D M Albert, C Ni

    Archives of Ophthalmology (Chicago, Ill. : 1960)
    |February 1, 1984
    PubMed
    Summary
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    Oxyphil cell adenomas, also known as oncocytomas, are rare tumors typically found in elderly women. These lacrimal sac and caruncle lesions are effectively managed with wide local excision.

    Area of Science:

    • Ophthalmology
    • Pathology

    Background:

    • Oxyphil cell adenomas (oncocytomas) are benign neoplasms characterized by abundant eosinophilic granular cytoplasm.
    • These tumors can occur in various locations, including the lacrimal system.

    Observation:

    • This report details three cases of oxyphil cell adenomas: two in the lacrimal sac and one in the caruncle.
    • The lesions presented with typical clinical and histopathologic features of oncocytomas.

    Findings:

    • The observed cases align with the general predilection for oncocytomas to affect the caruncle in elderly women.
    • While commonly found in the caruncle, these tumors can also involve the conjunctiva, lacrimal sac, and occasionally the lacrimal gland.

    Implications:

    • Wide local excision is an effective treatment modality for these lesions.

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  • Understanding the typical presentation and location aids in accurate diagnosis and management of lacrimal oncocytomas.