Related Experiment Video
Updated: Oct 7, 2026

06:38
Determination of Reproductive Competence by Confirming Pubertal Onset and Performing a Fertility Assay in Mice and Rats
Published on: October 13, 2018
Effects of prazosin on fertility of male rats
Journal of Reproduction and Fertility
|March 1, 1984
Abstract:
Silastic rods containing 25% or 50% prazosin HCl were inserted adjacent to the epididymis of rats. Silastic collars containing 25% prazosin HCl were placed around the vas deferens of rats. Treated males were infertile or subfertile for 6-9 weeks after insertion of these rods or collars. The number of spermatozoa observed in the vaginal smears was reduced. It is concluded that the antifertility effect of prazosin results mainly from inhibition of ejaculation.

