Surface proteins of scleroderma fibroblasts in culture

Scleroderma skin fibroblasts, as examined by a lactoperoxidase-iodine labeling technique, lack a surface associated protein of apparent molecular weight 120,000 daltons present in normal skin fibroblasts and contain 2 proteins 74,000 and 59,500 daltons, which are absent in normal-fibroblasts. Relative concentrations of several other cell surface proteins also appear to be different in these fibroblasts.