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Pyogenic liver abscess caused by Streptococcus milleri. Case reports
Abstract:
In recent years Streptococcus milleri has emerged as an important cause of pyogenic liver abscess. Whether this represents a changing epidemiological pattern or merely reflects the more widespread application of routine anaerobic bacterial culture techniques is unclear. The isolation of Strept. milleri on culture of a blood specimen from a patient presenting with a pyrexial illness should alert the clinician to the possibility of an underlying liver abscess. Although it is isolated anaerobically this organism should not be mistaken for an obligate anaerobe, especially since it is resistant to metronidazole. Two cases of primary pyogenic liver abscess caused by this organism are reported.
Insights
Streptococcus milleri is increasingly recognized as a cause of pyogenic liver abscess. Early identification from blood cultures is crucial for prompt diagnosis and treatment of this serious infection.
Area of Science:
- Microbiology
- Infectious Diseases
- Hepatology
Background:
- Pyogenic liver abscesses are serious infections.
- Streptococcus milleri is an emerging pathogen in liver abscesses.
- Diagnostic methods for anaerobic bacteria are becoming more common.
Observation:
- Streptococcus milleri is increasingly isolated from patients with pyogenic liver abscess.
- The organism is often isolated from blood cultures in patients with fever.
- Clinicians should consider liver abscess when Streptococcus milleri is detected.
Findings:
- Streptococcus milleri is a significant cause of pyogenic liver abscess.
- This organism is not an obligate anaerobe and is resistant to metronidazole.
- Two cases of primary pyogenic liver abscess caused by Streptococcus milleri are presented.
Implications:
- Routine anaerobic culture may increase the detection of Streptococcus milleri as a cause of liver abscess.
- Awareness of Streptococcus milleri's role is important for diagnosis and treatment.
- Metronidazole should not be relied upon for treating infections caused by this organism.
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