Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

HLA polymorphisms in a Shanghai Chinese population.

D Jaraquemada, A Alonso, J Awad

    Tissue Antigens
    |January 1, 1984
    PubMed
    Summary

    This study determined human leukocyte antigen (HLA) antigen frequencies in a Shanghai Chinese population. Significant differences were observed compared to other Chinese groups, highlighting the need for studies on homogeneous populations.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Compartmentalization of ceramide signaling: physical foundations and biological effects.

    Journal of cellular physiology·2000
    Same author

    Oscillatory activity in entorhinal neurons and circuits. Mechanisms and function.

    Annals of the New York Academy of Sciences·2000
    Same author

    [VIGILA: a tool for the epidemiologic surveillance of transmissible diseases].

    Revista cubana de medicina tropical·2000
    Same author

    HLA-DR51 expression failure caused by a two-base deletion at exon 2 of a DRB5 null allele (DRB5*0110N) in a Spanish gypsy family.

    Tissue antigens·2000
    Same author

    Stenotrophomonas maltophilia D457R contains a cluster of genes from gram-positive bacteria involved in antibiotic and heavy metal resistance.

    Antimicrobial agents and chemotherapy·2000
    Same author

    A randomized field trial of ACINDES: a child-centered training model for children with chronic illnesses (asthma and epilepsy).

    Journal of urban health : bulletin of the New York Academy of Medicine·2000

    Area of Science:

    • Immunogenetics
    • Population genetics

    Background:

    • Human leukocyte antigen (HLA) antigen frequencies vary significantly across different populations.
    • Previous studies on Chinese populations have not always accounted for subgroup heterogeneity.

    Purpose of the Study:

    • To determine the frequencies of HLA-A, B, C, D, DR, and MB antigens in a homogeneous Shanghai Chinese population.
    • To compare these frequencies with existing data from other Chinese subsets.
    • To emphasize the importance of studying homogeneous populations to avoid confounding factors.

    Main Methods:

    • Serological typing was used to determine the frequencies of HLA antigens.
    • Data analysis involved comparing antigen frequencies between the Shanghai Chinese group and other reported Chinese populations.

    Related Experiment Videos

    Main Results:

    • Significant differences in HLA-A and HLA-B antigen frequencies were found between the Shanghai Chinese and other Chinese population subsets.
    • No prior data were available for comparison for HLA-D, DR, and MB antigens in Chinese populations.

    Conclusions:

    • Population heterogeneity can significantly impact HLA antigen frequency studies.
    • Future research on Chinese populations should focus on clearly defined, homogeneous subsets to ensure accurate and comparable results.
    • Understanding HLA diversity within homogeneous groups is crucial for various applications, including transplantation and disease association studies.