[Changes in systemic and cerebral hemodynamics in patients with chronic cerebral circulatory insufficiency of atherosclerotic origin]
Related Experiment Videos
Insights
This study on chronic disorders of cerebral blood circulation (CDCBC) found that compensated insufficiency involves higher blood pressure and heart rate. Rheoencephalography revealed distinct changes in cerebral blood flow across different CDCBC stages.
Area of Science:
- Neurology
- Cardiovascular Science
- Medical Diagnostics
Context:
- Atherosclerosis impacts cerebral blood circulation.
- Chronic disorders of cerebral blood circulation (CDCBC) present varied hemodynamic profiles.
- Understanding CDCBC progression is crucial for patient management.
Purpose:
- To investigate systemic hemodynamics and rheoencephalographic (REG) parameters in atherosclerotic patients with CDCBC.
- To correlate hemodynamic and cerebral circulation changes with the stage of CDCBC.
- To assess the utility of REG in evaluating cerebral blood flow alterations.
Summary:
- Fifty atherosclerotic patients with CDCBC were studied for systemic hemodynamics and REG parameters.
- Compensated CDCBC showed increased arterial pressure, hand-ear blood flow velocity, and heart rate.
- REG findings indicated progressive deepening of cerebral circulation changes from compensatory to decompensated stages, particularly in the carotid and vertebral-basal basins.
Impact:
- Provides insights into the hemodynamic and rheoencephalographic changes associated with different stages of CDCBC.
- Highlights the potential of REG as a diagnostic tool for assessing cerebral blood flow in atherosclerotic patients.
- Informs clinical understanding and management strategies for chronic cerebrovascular disorders.
Abstract:
Fifty atherosclerotic patients with chronic disorders of the cerebral blood circulation (CDCBC) were involved in this study of both systemic hemodynamics (by diluting Evans blue) and rheoencephalographic parameters of the cerebral circulation with regard to the stage of the CDCBC. Compensated vascular-cerebral insufficiency was associated with a significant rise in the arterial pressure, acceleration of the blood flow in the hand-ear region and with an increase in the heart rate. Visual and amplitude-frequency characteristics of REGs in a compensatory stage of the CDCBC deepened only slightly; in a remitting stage they deepened significantly in the left carotid and vertebral-basal basins; in a subcompensated stage, in both basins bilaterally; and in a decompensated stage, predominantly in the carotid basin.