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Chronic multifocal symmetrical osteomyelitis. Report of two cases in Bedouin infants
Insights
Chronic multifocal symmetrical osteomyelitis, a rare bone condition, was observed in two young Bedouin children. This finding expands the known demographic profile of this benign disease, showing good prognosis.
Area of Science:
- Pediatric Orthopedics
- Rheumatology
- Radiology
Background:
- Chronic multifocal symmetrical osteomyelitis (CFSO) is a rare condition.
- Characterized by multiple, symmetrical bone lesions with a benign course.
- Previously reported exclusively in patients of European ancestry.
Observation:
- Two Bedouin children, aged 20 and 21 months, presented with symptoms.
- Clinical presentation included a painful joint.
- Radiological examination revealed multiple osteolytic lesions in long bones.
Findings:
- The cases represent the first reported occurrence of CFSO in non-European ancestry patients.
- Both children exhibited multiple symmetrical osteolytic lesions.
- A six-month follow-up showed complete recovery without radiological sequelae.
Implications:
- This study broadens the known ethnic distribution of CFSO.
- Highlights the importance of considering CFSO in diverse pediatric populations.
- Suggests CFSO has a favorable prognosis across different ethnicities.
Abstract:
Chronic multifocal symmetrical osteomyelitis is a rare condition characterized clinically and radiologically by multiple symmetrical bone lesions, a benign course, and a good prognosis. To our knowledge, only 25 cases have been reported in the literature; all of them occurred in patients of European ancestry. We describe two bedouin children, aged 20 and 21 months, who suffered from this disease. Although they complained of one painful joint, multiple osteolytic lesions were found in the long bones. At follow-up six months later, the children were in perfect condition without radiologic sequelae.