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Creatine kinase elevation after scleral buckling.

Annals of Ophthalmology

|January 1, 1984

Summary

This summary is machine-generated.

Postoperative patients after scleral buckling showed elevated creatine kinase levels, primarily from skeletal muscle (CK-MM), not heart muscle (CK-MB). Isoenzyme testing is advised if myocardial infarction is suspected.

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Area of Science:

Ophthalmology
Clinical Biochemistry

Background:

Scleral buckling is a surgical procedure to repair retinal detachments.
Elevated serum creatine kinase (CK) levels can indicate tissue damage.

Observation:

Patients undergoing scleral buckling exhibited a two- to three-fold increase in serum CK levels postoperatively.
Analysis of CK isoenzymes revealed the absence of the myocardial fraction (CK-MB).

Findings:

The observed elevation in serum CK was attributed to the skeletal muscle fraction (CK-MM).
This suggests that the elevated CK levels were not indicative of cardiac muscle injury.

Implications:

Routine CK level monitoring post-scleral buckling may lead to misinterpretation without isoenzyme analysis.

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CK isoenzyme testing is crucial in postoperative patients to differentiate skeletal from myocardial sources of elevation, especially when myocardial infarction is a concern.