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Related Experiment Videos

Onchocerciasis in Israel.

D Rozenman, M Kremer, F Zuckerman

    Archives of Dermatology
    |April 1, 1984
    PubMed
    Summary

    A 15-year-old boy experienced severe itching due to onchocerciasis, a parasitic worm infection. Diagnosis in a non-endemic area highlights challenges in identifying diseases in travelers.

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    Area of Science:

    • Medical Parasitology
    • Tropical Medicine
    • Dermatology

    Background:

    • Onchocerciasis, also known as river blindness, is a neglected tropical disease caused by the filarial nematode Onchocerca volvulus.
    • It is endemic in sub-Saharan Africa and parts of Central and South America.
    • Increased global travel facilitates the spread of infectious diseases to non-endemic regions.

    Observation:

    • A 15-year-old male immigrant from Ethiopia presented with a five-month history of severe generalized pruritus.
    • The patient had relocated to Israel, a region where onchocerciasis is not endemic.
    • Physical examination revealed areas of depigmentation on the right thigh.

    Findings:

    • A skin biopsy from the depigmented area on the thigh confirmed the presence of Onchocerca volvulus microfilariae in the dermis.
    • This finding established the diagnosis of onchocerciasis.

    Implications:

    • The case underscores the importance of considering onchocerciasis in the differential diagnosis of pruritic skin conditions, even in non-endemic areas.
    • Globalization and ease of travel necessitate heightened awareness among clinicians for diagnosing imported diseases.
    • This highlights the diagnostic challenges posed by the increasing geographic distribution of diseases due to international migration.

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