Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Monomelic amyotrophy.

M Gourie-Devi, T G Suresh, S K Shankar

    Archives of Neurology
    |April 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    This study identifies a rare neurological condition causing muscle wasting and weakness in a single limb. The condition, affecting younger adults, progresses slowly and remains confined to the affected limb.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Silver Jubilee Year of Annals of Indian Academy of Neurology: Commemorative Volume.

    Annals of Indian Academy of Neurology·2022
    Same author

    Brain banking in India: Relevance in current day practice.

    Indian journal of pathology & microbiology·2022
    Same author

    Association of Infantile Spasms and Hypsarrhythmia with Primary Microcephaly- Three Case Reports.

    Annals of Indian Academy of Neurology·2021
    Same author

    Is Perls Prussian Blue Stain for Hemosiderin a Useful Adjunct in the Diagnosis of Vasculitic Neuropathies?

    Neurology India·2021
    Same author

    Enigma of tropical spastic paraplegia.

    Neurology India·2020
    Same author

    Circle of Willis abnormalities and their clinical importance in ageing brains: A cadaveric anatomical and pathological study.

    Journal of chemical neuroanatomy·2020
    Same journal

    Incorrect Table Entries and Word.

    Archives of neurology·2016
    Same journal

    IDEAL for CCSVI Research-Reply.

    Archives of neurology·2013
    Same journal

    Atlas of Inherited Metabolic Diseases, 3rd ed.

    Archives of neurology·2013
    Same journal

    Error in byline: in heterogeneity of coenzyme q10 deficiency: patient study and literature review.

    Archives of neurology·2013
    Same journal

    This month in archives of neurology.

    Archives of neurology·2013
    Same journal

    About this journal.

    Archives of neurology·2013
    See all related articles

    Area of Science:

    • Neurology
    • Clinical Neuroscience
    • Neurodegenerative Diseases

    Background:

    • Single-limb atrophy is a rare condition characterized by muscle wasting and weakness.
    • Previous studies have not fully elucidated the clinical and electrophysiological features of this condition.

    Purpose of the Study:

    • To describe the clinical, electrophysiological, and histological features of patients with single-limb atrophy.
    • To investigate the progression and long-term outcomes of this condition.

    Main Methods:

    • A retrospective analysis of 23 patients diagnosed with single-limb atrophy between 1977 and 1981.
    • Clinical examination, electromyography (EMG), and muscle biopsy were performed.

    Main Results:

    Related Experiment Videos

  • The study identified 23 patients (13 upper-limb, 10 lower-limb) with insidious onset in their second and third decades.
  • Key features included male preponderance, sporadic occurrence, and weakness confined to one limb, with no cranial nerve, central nervous system, or sensory involvement.
  • Electromyography and histology indicated an anterior horn cell lesion, with slow progression over 2-4 years followed by a stable phase.

    • Conclusions:

    • Single-limb atrophy is a distinct neurological entity likely originating from anterior horn cell damage.
    • The condition presents with a characteristic pattern of localized weakness and slow progression, remaining confined to one limb even after 10-15 years.