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Updated: Aug 17, 2026

Determining heat and mechanical pain threshold in inflamed skin of human subjects
Published on: January 14, 2009
[Comparison of diflunisal and tilidine in tumor pain]
Abstract:
In an open study in patients with tumour-induced pain the analgetic effects of the prostaglandin-inhibiting compound diflunisal and the centrally-acting analgetic tilidine N were compared. A dosage of 1 g diflunisal was found to be equivalent to 50 drops of tilidine N and to be subjectively well-tolerated. In the pain-relieving therapy of tumour patients diflunisal appears to offer a genuine alternative to centrally-acting analgetics.
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