Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Availability of glucose given orally during exercise.

G Krzentowski, B Jandrain, F Pirnay

    Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology
    |February 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Complementarity between randomised controlled trials and observational registries : the example of cardiovascular prevention with SGLT2 inhibitors].

    Revue medicale de Liege·2017
    Same author

    [STRENGTHS AND WEAKNESSES OF RANDOMISED CLINICAL TRIALS: EVOLVING CHANGES ACCORDING TO PERSONALIZED MEDICINE].

    Revue medicale de Liege·2015
    Same author

    [How I explore ... a risk difference in the occurrence of an event in clinical trials].

    Revue medicale de Liege·2013
    Same author

    [Pulmonary rehabilitation in chronic obstructive pulmonary disease].

    Revue medicale de Liege·2008
    Same author

    [Blood glucose control and cardiovascular disease in patients with type 2 diabetes. Results of ACCORD, ADVANCE and VA-Diabetes trials].

    Revue medicale de Liege·2008
    Same author

    [The new insulins].

    Revue medicale de Bruxelles·2005

    Ingesting oral glucose during prolonged exercise effectively fuels the body, with similar utilization rates whether taken early or late. This study clarifies glucose metabolism during extended physical activity.

    Area of Science:

    • Exercise Physiology
    • Nutritional Science
    • Metabolic Research

    Background:

    • Oral glucose utilization during prolonged exercise is debated.
    • Understanding timing of glucose intake is crucial for athletes and endurance performance.

    Purpose of the Study:

    • To determine if the timing of oral glucose ingestion affects exogenous glucose disposal during prolonged exercise.
    • To investigate the impact of exercise duration on glucose metabolism and oxidation.

    Main Methods:

    • Nine healthy males underwent 4-hour treadmill exercise at 45% maximum oxygen consumption.
    • A 100g [13C]glucose load was administered either 15 minutes (Group B) or 120 minutes (Group A) into the exercise.
    • Indirect calorimetry measured substrate oxidation; blood glucose and C-peptide levels were monitored.

    Related Experiment Videos

    Main Results:

    • Total carbohydrate and lipid oxidation were similar between groups post-ingestion.
    • Exogenous glucose oxidation rates were comparable (approx. 55% of load within 2 hours) regardless of ingestion timing.
    • Blood glucose response was similar, but C-peptide response was blunted when glucose was ingested later in exercise.

    Conclusions:

    • Oral glucose is effectively oxidized during moderate-intensity prolonged exercise.
    • Glucose utilization is not significantly affected by ingestion timing (15 vs. 120 minutes into exercise).
    • Later glucose ingestion may lead to a reduced insulin response during exercise.