A backcross method to prevent prenatal death of steel mutant mice

Homozygous Sl/Sl mice survive until adulthood when obtained from matings between WC/Re-Sl/+ and (WC/Re X Swiss:NIH) F1-Sl/+ or WC/Re-Sl/+ and (WC/Re X AKR/Cum) F1-Sl/+ mice. They possess the classical hematological abnormalities produced by mutations at the Sl locus.