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Updated: Aug 14, 2026

Reproducable Paraplegia by Thoracic Aortic Occlusion in a Murine Model of Spinal Cord Ischemia-reperfusion
Published on: March 3, 2014
Spinal cord injury associated with hyperthermia during aortic coarctation repair
Abstract:
Three infants with coarctation of the thoracic aorta, patent ductus arteriosus (PDA), and ventricular septal defect (VSD) underwent repair of the coarctation in three different institutions. Despite a technically uncomplicated operation, each was noted to have significant paraplegia postoperatively. Retrospective analysis revealed that each patient had been hyperthermic during the time of aortic cross-clamping. It is possible that the hyperthermia, either alone or in combination with other factors, contributed to the development of paraplegia in these three infants.
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