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Related Experiment Videos

Coughs cause systemic blood flow.

J M Cary, R Krugmeier, B Newman

    Thorax
    |March 1, 1984
    PubMed
    Summary
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    Rhythmic coughing can generate forward arterial blood flow in humans. The vigor of the cough directly correlates with the magnitude of this effort-dependent increase in blood flow.

    Area of Science:

    • Cardiovascular Physiology
    • Neurology

    Background:

    • Rhythmic coughing is known to maintain consciousness during cardiac arrhythmias like ventricular fibrillation.
    • The direct impact of coughing on arterial pressure transients and forward blood flow in humans remains incompletely understood.

    Purpose of the Study:

    • To investigate the effectiveness of voluntary coughing in generating forward arterial blood flow in healthy individuals.
    • To determine if the magnitude of cough-induced blood flow correlates with cough effort.

    Main Methods:

    • Eight healthy volunteers with induced bradycardia performed voluntary coughs between cardiac cycles.
    • Oesophageal balloon manometry measured cough force; Doppler velocimetry and photoplethysmography assessed radial artery blood flow.
    • Brachial artery occlusion was used to mitigate motion artifacts in Doppler recordings.

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    Main Results:

    • Coughing significantly increased the area under Doppler and photoplethysmograph pulse flow tracings compared to non-coughing beats.
    • The augmentation of arterial blood flow was significantly greater with more forceful coughs.
    • A clear effort-dependent relationship was observed between cough vigor and forward flow pulses.

    Conclusions:

    • Voluntary coughing generates a measurable forward pulse of blood flow within the arterial circulation.
    • The intensity of the cough effort directly influences the extent of the resulting forward blood flow.
    • These findings support the physiological mechanism by which coughing can sustain circulation during certain cardiac events.