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Related Experiment Videos

Progressive retinal degeneration in ranch mink.

W J Hadlow

    Veterinary Pathology
    |January 1, 1984
    PubMed
    Summary

    Retinal degeneration affected 78% of mink over two years old. This condition primarily impacted photoreceptors, with sapphire mink showing higher prevalence and severity than pastel mink.

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    Area of Science:

    • Veterinary Ophthalmology
    • Animal Pathology

    Background:

    • Retinal degeneration was observed in sapphire and pastel mink (Mustela vison).
    • The condition was prevalent in mink aged two to eight years, affecting nearly 78% of the population.

    Purpose of the Study:

    • To characterize the prevalence and pathological features of retinal degeneration in mink.
    • To investigate potential differences in retinopathy between sapphire and pastel mink breeds.

    Main Methods:

    • Histopathological examination of retinal tissues using light microscopy.
    • Assessment of retinopathy prevalence and severity based on mink age, sex, and color variant.

    Main Results:

    • Retinopathy occurred in 78% of mink aged 2-8 years, with higher prevalence (85%) and severity in sapphire mink compared to pastel mink (63%).
    • Primary pathological changes included progressive degeneration of photoreceptors (rods and cones) starting in the outer segments.
    • Inner retinal layers and pigment epithelium remained largely unaffected until late stages.

    Conclusions:

    • The study identified a significant prevalence of retinal degeneration in mink, particularly affecting photoreceptors.
    • The cause remains undetermined, but may involve an abiotrophy or age-related photoreceptor degradation.
    • This retinopathy has implications for mink vision, fur, and reproductive cycles due to their light sensitivity.

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