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Central serous chorioretinopathy complicating systemic corticosteroid treatment
The British Journal of Ophthalmology
|May 1, 1984
Summary
Systemic corticosteroid treatment can cause central serous chorioretinopathy in patients with retrobulbar neuritis. Reducing steroid dosage may lead to spontaneous recovery, suggesting corticosteroids may harm the blood-ocular barrier.
Area of Science:
- Ophthalmology
- Neuro-ophthalmology
Background:
- Retrobulbar neuritis is an inflammatory condition affecting the optic nerve.
- Corticosteroids are commonly used to manage inflammatory and autoimmune conditions.
Observation:
- Two cases of central serous chorioretinopathy (CSCR) emerged during systemic corticosteroid therapy for retrobulbar neuritis.
- Fluorescein angiography revealed retinal pigment epithelium leakage and detachment in affected eyes.
Findings:
- CSCR resolved with decreased corticosteroid dosage in one patient, recurring with higher doses.
- The findings suggest a potential link between high-dose corticosteroids and the development of CSCR.
Implications:
- High-dose systemic corticosteroids may compromise the posterior blood-ocular barrier.
- Ophthalmologists should monitor for CSCR in patients treated with systemic corticosteroids, especially for retrobulbar neuritis.