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[Aggressive fibromatoses].

J R Döhler, H Hamelmann, U Lasson

    Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen
    |March 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Aggressive fibromatoses, or desmoid tumors, are benign but challenging to treat, often recurring after surgery. Spontaneous regression is possible, highlighting the need to weigh treatment risks against potential benefits.

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    Area of Science:

    • Oncology
    • Surgical Pathology
    • Orthopedic Oncology

    Background:

    • Aggressive fibromatoses (desmoid tumors) present therapeutic challenges similar to malignant neoplasms.
    • These benign tumors exhibit a propensity for local recurrence following incomplete surgical resection.

    Observation:

    • Seven patient cases illustrate the complexities of desmoid tumor management.
    • Five cases involved primary bone affliction, underscoring skeletal involvement.
    • Detailed reports highlight varied clinical trajectories, including radiation-induced malignant transformation and spontaneous regression.

    Findings:

    • Subtotal resection of desmoid tumors is frequently associated with recurrence.
    • Spontaneous regression, though possible, is not a predictable outcome.

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  • Aggressive surgical interventions like hemipelvectomy and limb amputation may not achieve definitive cure.

    • Implications:

    • Treatment decisions for desmoid tumors require careful consideration of recurrence risk and potential morbidity.
    • The possibility of spontaneous regression warrants conservative management approaches in select cases.
    • Further research into optimal therapeutic strategies for aggressive fibromatoses is essential.