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Necrotizing enterocolitis beyond the neonatal period.

R Dagan, O Ben-Yacov, A J Mares

    European Journal of Pediatrics
    |April 1, 1984
    PubMed
    Summary

    Necrotizing enterocolitis (NEC) in infants beyond the neonatal period is rare but associated with high mortality. Malnutrition appears to be a significant contributing factor to both NEC development and poor outcomes in this age group.

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    Area of Science:

    • Pediatrics
    • Neonatology
    • Gastroenterology

    Background:

    • Necrotizing enterocolitis (NEC) is predominantly recognized as a neonatal condition.
    • Limited data exists on NEC presentation and outcomes in infants beyond the neonatal period.

    Purpose of the Study:

    • To investigate the characteristics, risk factors, and outcomes of infants diagnosed with NEC outside the neonatal age group.

    Main Methods:

    • Retrospective review of 19 infants diagnosed with NEC between 34 and 616 days of age.
    • Analysis of clinical data including prematurity, perinatal history, preceding symptoms, bacteremia, and nutritional status.

    Main Results:

    • Only 16% of infants were premature, and 16% had prior neonatal pathology.

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  • Diarrhea, dehydration, and malnutrition were common preceding conditions.
  • Bacteremia was present in 42% of cases.
  • The overall mortality rate was a striking 90%.
  • Conclusions:

    • NEC occurring beyond the neonatal period is uncommon and characterized by severe outcomes.
    • Malnutrition is a potential key factor in the pathogenesis and high mortality of NEC in this older infant population.