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Platelet-derived growth factor (PDGF) induces intranuclear protein accumulation in 3T3 fibroblasts
Experimental Cell Research
|May 1, 1984
Abstract:
Quiescent 3T3 fibroblasts were grown for a short time in the presence of [3H]amino acids then treated with PDGF, and the nucleo-cytoplasmic distribution of the 3H-labelled proteins was analysed by autoradiography. There was no difference in the total amount of 3H-labelled proteins in PDGF-treated and untreated cells but PDGF induced a significant increase in intranuclear protein accumulation.