Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lipid peroxidation in rabbit reticulocytes.

Y Kobayashi, T Usui

    Experientia
    |April 15, 1984
    PubMed
    Summary

    Lipid peroxides in rabbit blood cells and plasma increase during induced anemia. These levels normalize as red blood cells mature, indicating a link between red blood cell development and lipid peroxidation.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Molecular cloning and expression of multiple isoforms of human prostaglandin E receptor EP3 subtype generated by alternative messenger RNA splicing: multiple second messenger systems and tissue-specific distributions.

    Molecular pharmacology·1995
    Same author

    Long-term results with M-VAC for advanced urothelial cancer: high relapse rate and low survival in patients with a complete response.

    British journal of urology·1995
    Same author

    A K-252a-resistance gene, sks1+, encodes a protein similar to the Caenorhabditis elegans F37 A4.5 gene product and confers multidrug resistance in Schizosaccharomyces pombe.

    Gene·1995
    Same author

    Trends in antimicrobial resistance of Streptococcus pneumoniae in Japan.

    Antimicrobial agents and chemotherapy·1995
    Same author

    Structural organization and chromosomal assignment of the human prostacyclin receptor gene.

    Genomics·1995
    Same author

    [Case of Creutzfeldt-Jakob disease with the development of Gerstmann syndrome at its onset].

    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine·1995

    Area of Science:

    • Hematology
    • Biochemistry
    • Red Blood Cell Biology

    Background:

    • Anemia is a condition characterized by a deficiency of red blood cells or hemoglobin.
    • Lipid peroxidation is a process that damages cells and is associated with various pathological conditions.
    • Understanding the biochemical changes during anemia is crucial for developing effective treatments.

    Purpose of the Study:

    • To investigate the changes in lipid peroxide levels in rabbit erythrocytes and plasma during induced anemia.
    • To correlate lipid peroxide levels with the increase in reticulocytes and their subsequent maturation.

    Main Methods:

    • Anemia was induced in rabbits through daily bleeding.
    • Lipid peroxide levels in erythrocytes and plasma were measured.
    • Reticulocyte counts and red blood cell morphology were analyzed.

    Main Results:

    • Lipid peroxide levels in erythrocytes and plasma were elevated during the period of induced anemia.
    • The increase in lipid peroxides correlated with the rise in reticulocyte counts.
    • As reticulocytes transformed into mature erythrocytes, lipid peroxide levels returned to normal.

    Conclusions:

    • Lipid peroxidation is associated with the dynamic changes in red blood cell production and maturation during anemia.
    • The study suggests that young red blood cells (reticulocytes) may be more susceptible to lipid peroxidation.
    • These findings contribute to understanding the oxidative stress associated with anemia.

    Related Experiment Videos