Related Experiment Videos
Synthesis and antiallergic activity of some mono- and disubstituted xanthone-2-carboxylic acids
Journal of Medicinal Chemistry
|July 1, 1978
Abstract:
A series of xanthone-2-carboxylic acids, substituted mainly with electron-withdrawing groups, has been synthesized and assayed for antiallergic activity, using the passive cutaneous anaphylaxis (PCA) reaction in the rat. The effect of substituent type and substitution pattern on PCA neutralizing capacity is presented.