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Related Experiment Videos

Circulatory failure in acute pulmonary embolism.

Y Ozier, O Dubourg, J C Farcot

    Intensive Care Medicine
    |January 1, 1984
    PubMed
    Summary

    Massive pulmonary embolism can cause circulatory failure due to pulmonary arterial obstruction. Echocardiography reveals right heart strain and unchanged left ventricular systolic function, though diastolic function may be impaired.

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    Area of Science:

    • Cardiology
    • Pulmonology
    • Medical Imaging

    Background:

    • Pulmonary embolism (PE) affects 10% of patients, causing circulatory failure via massive pulmonary artery obstruction.
    • Established hemodynamic and respiratory features include pulmonary hypertension, low cardiac output, elevated right ventricular filling pressures, and venous admixture.
    • Recent advancements allow visualization of cardiac changes using echocardiography.

    Purpose of the Study:

    • To detail the hemodynamic and echocardiographic findings in patients experiencing circulatory failure due to massive pulmonary embolism.
    • To assess the impact of massive pulmonary embolism on both right and left ventricular function.

    Main Methods:

    • Utilized two-dimensional echocardiography to visualize cardiac structures and function.

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  • Analyzed hemodynamic and respiratory parameters associated with pulmonary embolism.

    • Main Results:

    • Echocardiography demonstrated pulmonary artery and right heart enlargement, reduced right ventricular ejection fraction, and tricuspid regurgitation.
    • Left ventricular systolic function remained unchanged.
    • Potential reduction in left ventricular diastolic function was observed, attributed to septal bulging.

    Conclusions:

    • Massive pulmonary embolism significantly impacts right heart function, as evidenced by echocardiographic findings.
    • While left ventricular systolic function is preserved, diastolic function may be compromised due to right ventricular pressure overload and septal deviation.