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Updated: Aug 7, 2026

Grafting of Beads into Developing Chicken Embryo Limbs to Identify Signal Transduction Pathways Affecting Gene Expression
Published on: January 17, 2016
An increase in cell-cell adhesion in the chick segmental plate results in a meristic pattern
Abstract:
Cell-cell adhesion in the anterior portion of the segmental plate plays an important role in the initiation of somitogenesis. Dissociated somites show a marked tendency to reassociate into somite-size clumps within a few hours after dissociation. Segmental plate cells show very little tendency to reassociate, even after 24 h in culture. The cells from the anterior portion of the segmental plate do show a tendency to reassociate. This supports the hypothesis that cell-cell adhesion between the cells in the anterior portion of the segmental plate plays a major role in the initiation of somitogenesis.
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