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Cervical myelography with iohexol.

P Nakstad, O Aaserud, A Helgetveit

    Neuroradiology
    |January 1, 1984
    PubMed
    Summary
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    Iohexol (Omnipaque) demonstrated excellent image quality in cervical myelography. This water-soluble contrast medium shows low neurotoxicity and is suitable for intrathecal use.

    Area of Science:

    • Neuroradiology
    • Medical Imaging
    • Pharmacology

    Background:

    • Cervical myelography requires safe and effective contrast media.
    • Evaluating new contrast agents like iohexol is crucial for improving diagnostic procedures.

    Purpose of the Study:

    • To assess the properties and neurotoxicity of iohexol (Omnipaque) in cervical myelography.
    • To determine the suitability of iohexol for intrathecal administration.

    Main Methods:

    • An open-label study was conducted involving 20 patients undergoing cervical myelography.
    • Iohexol (Omnipaque), a water-soluble contrast medium, was administered intrathecally.

    Main Results:

    • Excellent (70%) or good (30%) image quality was achieved in all cases.

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  • Headache occurred in 25% of patients.
  • Severe electroencephalogram (EEG) changes were not observed; overall EEG changes occurred in 20%.

    • Conclusions:

    • Iohexol exhibits favorable properties for cervical myelography.
    • The study supports existing evidence of iohexol's low neurotoxicity.
    • Iohexol is well-suited for intrathecal use in myelography.