Extremely high concentration of serum prostate-specific acid phosphatase in an untreated prostatic cancer patient

We report a patient having advanced prostatic cancer and serum immunoreactive prostate-specific acid phosphatase concentrations of up to 8.9 mg/l, which is more than 3000 times the upper limit of our health-associated reference interval. following orchiectomy, the enzyme concentration decreased to 1.5 mg/l in 5 days, and to 3.6 micrograms/l within 1.5 months and to 1.4 micrograms/l within 6 months.