[What does computer tomography and abdominal ultrasound studies accomplish in the staging of Hodgkin's disease?]

In a prospective series of 25 patients with early-stage Hodgkin's disease, abdominal assessment by computer tomogram and ultrasound was controlled by staging laparotomy. It was found that the probability of Hodgkin's disease increased with increasing diameter of the abdominal lymph nodes. 42% of the nodes between 16-20 mm in diameter had evidence of disease. Overall accuracy and specificity for the assessment of abdominal lymph nodes by CT and US was around 90%. Sensitivity was much lower than in other series, probably due to the fact that our patient sample was relatively small and consisted of patients in earlier stages with small lymph nodes. Assessment of lymph nodes by US is more, and assessment by CT less, dependent on individual factors. It is concluded that neither CT or US can replace staging laparotomy if precise information about abdominal lymph nodes is needed. Assessment of the spleen by CT and US is usually unreliable and needs histologic confirmation.