A case of ovarian endodermal sinus tumor associated with pregnancy

A case of a 25-year-old 2 gravida, 1 para pregnant woman in the 7th week of gestation who was concurrented with endodermal sinus tumor (EST) is presented. Simple hysterectomy with left salpingo-oophorectomy, wedge resection of the right ovary and omentectomy were done following D & C. Histological features were identical to those described for EST by Teilum. Cytological findings of imprinted smears were characterized by cuboidal or columnar cells with vacuoles, naked-looking cells of various sizes, and cells with an extremely large nucleus/cytoplasm (N/C) ratio. Measurements were made on serum alpha-feto-protein and immunosuppressive acidic protein. The frequency of malignant ovarian tumors associated with pregnancy in the literature and at our clinic, and the treatment for it were discussed.