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[Iatrogenic histopathological findings. A systematic compilation].

R Vock

    Zeitschrift Fur Rechtsmedizin. Journal of Legal Medicine
    |January 1, 1984
    PubMed
    Summary
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    Drugs and diagnostic agents leave traceable histological changes in human organs. These iatrogenic alterations aid forensic medicine in identification, damage assessment, and evaluating drug abuse.

    Area of Science:

    • Forensic Pathology
    • Toxicology
    • Histology

    Context:

    • Drugs and diagnostic agents deposit in human organs, causing histological changes.
    • These iatrogenic alterations are often detectable shortly after administration and persist for varying durations.
    • Morphological evidence of drug deposition is relevant in forensic and legal contexts.

    Purpose:

    • To review drugs and diagnostic agents and their associated morphological alterations in human organs.
    • To detail histological demonstration methods and the duration of identifiability of these drug-induced changes.
    • To highlight the forensic significance of iatrogenic organ alterations.

    Summary:

    • A systematic review categorizes drugs and diagnostic agents by organ.
    • It details the specific morphological changes induced by these substances.

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  • Methods for histological identification and the persistence of these changes are discussed.

    • Impact:

    • Provides a reference for identifying unknown cadavers or tissues.
    • Assists in establishing iatrogenic damage in legal cases.
    • Supports the evaluation of findings in sudden deaths and insurance claims related to drug abuse, particularly analgesics.