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Abstract:
On the basis of the medical history and clinical examination of members of families of 133 practically healthy probands and probands suffering from ischemic heart disease and comparison of the frequency of this disease among: (1) husbands and wives and relatives of brother-sisters of probands with ischemic heart disease; (2) husbands and wives, living together for a long time, one of whom had a favourable heredity while the heredity of the other is aggravated by vascular and metabolic diseases; (3) step-borthers and step-sisters born of remarriage of a healthy person to another healthy person in one case and to a sick person in another; (4) persons related in different extent to a sick proband, the authors conclude that genetic factors are very important in the development of coronary atherosclerosis and ischemic heart disease.