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Left ventricular wall motion abnormalities in Kawasaki's disease.

E Grenadier, H D Allen, S J Goldberg

American Heart Journal

|May 1, 1984

Summary

Two-dimensional echocardiography (2DE) effectively detects cardiac involvement in Kawasaki's disease by identifying myocardial contraction deficits. While coronary aneurysms were visualized, 2DE showed greater sensitivity for assessing left ventricular contraction abnormalities.

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Area of Science:

Cardiology
Pediatric Cardiology
Diagnostic Imaging

Background:

Kawasaki's disease is a significant cause of acquired heart disease in children.
Cardiac involvement, including coronary artery abnormalities, can lead to serious complications.
Early and accurate detection of cardiac involvement is crucial for timely management.

Purpose of the Study:

To evaluate the utility of two-dimensional (2DE) and M-mode echocardiography in detecting cardiac abnormalities in patients with Kawasaki's disease.
To compare the effectiveness of echocardiography with other diagnostic methods for cardiac assessment in this population.

Main Methods:

Review of echocardiographic examinations (2DE and M-mode) in 21 patients with Kawasaki's disease.
Cardiac catheterization with coronary angiography performed in 14 patients for comparison.

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Analysis of findings including regional myocardial contraction deficits and coronary aneurysms.

Main Results:

2DE identified regional myocardial contraction deficits in four patients with confirmed coronary disease.
Echocardiography detected coronary aneurysms in two of four patients with coronary lesions.
M-mode echocardiography, ECG, and chest X-ray were not helpful in detecting cardiac involvement.

Conclusions:

2DE is a sensitive method for detecting cardiac involvement in Kawasaki's disease, particularly left ventricular (LV) wall contraction abnormalities.
2DE is more effective for assessing LV contraction than for imaging coronary aneurysms in Kawasaki's disease patients.