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[Aortic dissection and Horton's disease. 2 cases].

F Penin, J M Schmidt, J Froment

    Annales De Medecine Interne
    |January 1, 1984
    PubMed
    Summary
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    Temporal arteritis can complicate with aortic dissection. Steroid therapy showed favorable outcomes in two reported cases, suggesting inflammation

    Area of Science:

    • Vascular Surgery
    • Rheumatology
    • Pathology

    Background:

    • Temporal arteritis, a form of large-vessel vasculitis, is primarily associated with cranial arteries.
    • Aortic complications, though less common, represent a significant concern in patients with temporal arteritis.

    Observation:

    • Two cases of temporal arteritis presenting with dissecting aortic aneurysms are detailed.
    • One case was identified during routine physical examination; the other presented with acute thoracic pain.

    Findings:

    • Both patients experienced favorable clinical courses following treatment with corticosteroid therapy.
    • Literature review identified eleven additional cases with pathological confirmation of this complication.
    • Active inflammatory involvement of the aortic wall is proposed as the primary pathophysiological mechanism.

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    Implications:

    • Early detection and management of aortic complications are crucial in temporal arteritis patients.
    • Corticosteroid therapy appears effective in managing these complex cases.
    • Further research into the inflammatory pathways linking temporal arteritis and aortic disease is warranted.