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Related Experiment Videos

Neuromyelitis optica in the elderly.

C M Filley, P E Sternberg, M D Norenberg

    Archives of Neurology
    |June 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Neuromyelitis optica (NMO), a rare autoimmune disorder, can manifest in elderly individuals. This case highlights late-onset NMO, suggesting similar possibilities for multiple sclerosis in advanced age.

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    Area of Science:

    • Neuroimmunology
    • Neuropathology

    Background:

    • Neuromyelitis optica (NMO) is an inflammatory demyelinating disease primarily affecting the optic nerves and spinal cord.
    • While typically diagnosed in younger adults, late-onset presentations require further investigation.

    Observation:

    • An elderly woman developed blindness and quadriparesis starting at age 69.
    • Postmortem examination identified extensive demyelinative lesions in the optic nerves and spinal cord.

    Findings:

    • The clinical and pathological findings strongly supported a diagnosis of neuromyelitis optica (NMO).
    • This case demonstrates that NMO can present initially in advanced age.

    Implications:

    • This case suggests that late-onset NMO is a possibility in the elderly population.

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  • It also implies that typical multiple sclerosis may similarly have initial onset at an advanced age, challenging current diagnostic assumptions.