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A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
06:01

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

Left ventricular thrombosis and cerebrovascular accident in acute myocardial infarction

K A Johannessen, J E Nordrehaug, G von der Lippe

    British Heart Journal
    |May 1, 1984
    PubMed

    Insights

    Anterior wall myocardial infarction significantly increases the risk of left ventricular thrombosis, a condition linked to cerebrovascular accidents. Early diagnosis via echocardiography is crucial for managing this complication.

    Area of Science:

    • Cardiology
    • Internal Medicine

    Background:

    • Left ventricular thrombosis is a known complication of myocardial infarction.
    • Anterior wall myocardial infarction is associated with a higher risk of complications.

    Purpose of the Study:

    • To investigate the incidence and risk factors of left ventricular thrombosis in patients with acute myocardial infarction.
    • To determine the association between left ventricular thrombosis and cerebrovascular accidents.

    Main Methods:

    • Prospective study of 90 consecutive patients with acute myocardial infarction.
    • Cross-sectional echocardiography used to diagnose left ventricular thrombosis.
    • Analysis of patient history, cardiac imaging, and clinical outcomes.

    Main Results:

    • Left ventricular thrombosis occurred in 28.3% of patients with anterior wall infarction, but none with inferior infarction.
    • Four of five patients experiencing cerebrovascular accidents had pre-existing left ventricular thrombosis.
    • Apical akinesis was present in all patients with left ventricular thrombosis.

    Conclusions:

    • Large anterior wall myocardial infarction with apical akinesis identifies patients at high risk for left ventricular thrombosis.
    • Left ventricular thrombosis is a potential source of peripheral emboli, including cerebrovascular accidents.
    • Left ventricular thrombosis is rare in myocardial infarctions located elsewhere.

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