[Electrical activity of the cerebral cortex in fasting dogs with preserved and disordered gastric innervation]

Chronic experiments on 6 hungry dogs were made to record the motor periodicity of the stomach from fistulas in the fundal area and the electrocorticograms (ECoG) from bipolar electrodes implanted into cranial bones. Five months before experiments 2 dogs of the six were subjected to selective distal vagotomy. Analysis of 700 ECoGs allowed the conclusion to be made that apart from stereotyped periodicity of the frequency spectrum of the ECoG according to the phases of gastric motor periodicity cycles, in each successive cycle there add up unique compositions of 5 main ECoG frequencies, which do not recur in other cycles (within the range from 2 to 30 Hz) consequent on the asymmetry in electric activity of the right and left hemisphere cortex and on the phenomenon of migrating wave activation. Denervation of the gastroduodenal zone organs leads to substantial restitution and destabilization of the frequency spectrum of the ECoG, disorders in the regulation of migrating wave activation. It is suggested that the features of the ECoG described are linked with the enterogastric mechanisms of hunger motivation.