[Morphofunctional characteristics of an abdominal aorta autograft after surgery]

The reconstruction of the abdominal aorta transplant was studied in experiments with 40 mongrel dogs shortly after operation. One, 12 and 24 hours and on days 5 and 10 after operation the total amount of protein was measured in the aortic arch, in the thoracic part, in the plasty area and in the zones lying above and beneath the plasty area. Disc electrophoresis was used to examine the qualitative composition of proteins. The localization of acridine orange in the autotransplant wall was defined with the aid of fluorescent microscopy. The preparations were studied by scanning electron microscopy. Denervation and devascularization were found shortly after operation to provoke the reduction of endotheliocytes, formation of interendothelial "holes" favouring rapid imbibition with blood of the vascular wall, which in turn led to cell destruction in the auto-transplant by day 5 after operation. On the 8th 10th day there occurred irreversible changes in the collagen-elastic framework of the aorta.