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Thyrotoxic myopathy associated with subacute thyroiditis.

K Tajima, K Mashita, T Yamane

    Clinical Endocrinology
    |March 1, 1984
    PubMed
    Summary
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    Thyrotoxic myopathy can occur with subacute thyroiditis, not just Graves' disease. Prolonged thyrotoxic states in subacute thyroiditis may lead to significant muscle weakness and atrophy.

    Area of Science:

    • Endocrinology
    • Neuromuscular Disorders

    Background:

    • Thyrotoxic myopathy is typically associated with Graves' disease.
    • Subacute thyroiditis is an inflammatory condition of the thyroid gland.

    Observation:

    • A 35-year-old male presented with proximal muscle weakness and atrophy.
    • These myopathic symptoms developed during the course of subacute thyroiditis.

    Findings:

    • The patient's thyrotoxic symptoms and myopathy resolved as thyroid hormone levels normalized.
    • Resolution of myopathic symptoms occurred over an extended period.

    Implications:

    • Subacute thyroiditis, particularly when associated with a prolonged thyrotoxic state, can precipitate significant thyrotoxic myopathy.
    • This case expands the known clinical spectrum of thyrotoxic myopathy.

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  • Clinicians should consider thyrotoxic myopathy in patients with subacute thyroiditis and unexplained muscle weakness.