Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hydrogen peroxide as a topical hemostatic agent.

F M Hankin, S E Campbell, S A Goldstein

    Clinical Orthopaedics and Related Research
    |June 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Precision Mass Measurement of the Proton Dripline Halo Candidate ^{22}Al.

    Physical review letters·2024
    Same author

    Pregnancy-related outcomes in obstetric patients with pulmonary hypertension: a single-center retrospective cohort study.

    International journal of obstetric anesthesia·2023
    Same author

    Screening, assessment and management of perioperative malnutrition: a survey of UK practice.

    Perioperative medicine (London, England)·2021
    Same author

    Self-diffusion in two-dimensional quasimagnetized rotating dusty plasmas.

    Physical review. E·2019
    Same author

    Aerobic Dance Injuries.

    The Physician and sportsmedicine·2016
    Same author

    Dusty plasma cavities: Probe-induced and natural.

    Physical review. E, Statistical, nonlinear, and soft matter physics·2015

    Hydrogen peroxide effectively reduces blood and debris at the bone-cement interface in joint replacements. This hemostatic agent improves the bond between bone and methylmethacrylate, crucial for total joint arthroplasties.

    Area of Science:

    • Biomaterials Science
    • Orthopedic Surgery
    • Surgical Innovation

    Background:

    • The bone-cement interface is critical for the success of total joint arthroplasties.
    • Methylmethacrylate bone cement is widely used in joint replacement surgery.
    • Blood and debris at the interface can compromise implant fixation and longevity.

    Purpose of the Study:

    • To evaluate the hemostatic effectiveness of hydrogen peroxide.
    • To determine if hydrogen peroxide reduces blood and debris interposition at the bone-cement interface.
    • To assess the impact of hydrogen peroxide on the trabecular bone-methylmethacrylate interface.

    Main Methods:

    • A canine model (ten mongrel dogs) was used with six metaphyseal bone beds.
    • Three bone sites were treated with hydrogen peroxide; three served as saline-treated controls.

    Related Experiment Videos

  • Hemostatic effect was quantified by comparing blood loss per unit area per minute before and after treatment.

    • Main Results:

    • Hydrogen peroxide demonstrated significant hemostatic effectiveness.
    • Treatment with hydrogen peroxide reduced blood loss compared to saline controls.
    • A reduction in trapped blood and debris within the trabecular bone-methylmethacrylate interface was observed with hydrogen peroxide.

    Conclusions:

    • Hydrogen peroxide is an effective hemostatic agent for improving the bone-cement interface.
    • Its application can mitigate the interposition of blood and debris, potentially enhancing arthroplasty outcomes.
    • Further investigation into clinical applications for total joint arthroplasties is warranted.