Porencephalic congenital cysts with hydrocephalus

Child'S Brain
|January 1, 1984
PubMed

Insights

Porencephalic congenital cysts in children often present with neurological deficits. Surgical intervention, including shunts and plastic surgery, improved patient morbidity.

Area of Science:

  • Pediatric Neurology
  • Neurosurgery
  • Developmental Pediatrics

Background:

  • Porencephalic congenital cysts are rare brain malformations.
  • Early diagnosis and intervention are crucial for managing associated neurological deficits.

Purpose of the Study:

  • To review therapeutic criteria for porencephalic congenital cysts based on tomographic findings.
  • To evaluate the clinical presentation, diagnostic methods, and surgical outcomes in children with these cysts.

Main Methods:

  • Retrospective review of 10 children (6 male, 4 female) with porencephalic congenital cysts.
  • Analysis of clinical symptoms, preoperative imaging (X-ray, EEG, CT), and surgical procedures (peritoneal/atrial shunts, plastic surgery).

Main Results:

  • Most children presented with symptoms within the first 6 months of life.
  • Common symptoms included retarded psychomotor development, endocranial hypertension, macrocrania, motor deficits, and seizures.
  • CT scans revealed porencephalic cysts, ventricular dilatation, and midline shift in most patients.
  • Surgical interventions led to improved morbidity without mortality.

Conclusions:

  • Tomographic findings are essential for diagnosing and planning treatment for porencephalic cysts.
  • Surgical management, including shunting and plastic surgery, can effectively improve outcomes in affected children.
  • Multidisciplinary rehabilitation and anticonvulsive treatment are vital components of postsurgical care.
Abstract

Related Concept Videos

Anatomy of the Brain: Ventricles01:18

Anatomy of the Brain: Ventricles

There are hollow fluid-filled cavities known as ventricles deep inside the human brain. There are two lateral ventricles, one in each cerebral hemisphere, and each has three different projections — the anterior, inferior, and posterior horns visible from the lateral side. A thin membrane called the septum pellucidum separates the two lateral ventricles. The slender third ventricle in the diencephalon is connected to each lateral ventricle via a channel called the interventricular foramen. The...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Increased Intracranial Pressure l: Introduction01:14

Increased Intracranial Pressure l: Introduction

Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...
Increased Intracranial Pressure ll: Pathophysiology01:29

Increased Intracranial Pressure ll: Pathophysiology

Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...
Cerebral Edema l: Introduction01:19

Cerebral Edema l: Introduction

Cerebral edema is a pathological increase in brain water content that disrupts intracranial pressure regulation and impairs neurological function. Because the cranial vault is rigid, even modest increases in tissue volume can compromise cerebral perfusion, distort neural structures, and initiate secondary injury. Cerebral edema develops through four principal mechanisms: vasogenic, cytotoxic, interstitial, and ionic.Vasogenic EdemaVasogenic edema arises from disruption of the blood–brain...
Cerebral Edema ll: Pathophysiology01:22

Cerebral Edema ll: Pathophysiology

Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...