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Updated: Aug 11, 2026

Production of Disulfide-stabilized Transmembrane Peptide Complexes for Structural Studies
Published on: March 6, 2013
A new assignment of the disulfide linkage in stellacyanin
Abstract:
Which cysteine of apostellacyanine reacts with 4-vinylpyridine in 6 M guanidine-HC1 depends upon the pH. We infer that a disulfide switch occurs at higher pH and that in the native protein the disulfide bridge occurs between Cys-59 and Cys-93. Thus Cys-87, which is homologous to the cysteine ligands of azurin and plastocyanin, is available to bind copper.
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