[Oral theophylline therapy for dyspnea]

With regard to special situations in severe dyspnea 10 patients with reversible airway obstruction were studied to verify the effect of oral and systemic application of 193,2 mg Theophyllinmonohydrat and 46,8 mg Aethylendiamin as customary in the trade injection fluid (Euphyllin) on blood levels. In comparison both medications are bioaquivalent . The oral application yields with duration serum concentrations of theophylline higher than 5 mg/l but less than the postulated therapeutic levels from 10--20 mg/l.