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Related Experiment Videos

Priapism associated with trazodone therapy: case report.

M R Lansky, J Selzer

    The Journal of Clinical Psychiatry
    |May 1, 1984
    PubMed
    Summary

    Priapism, a prolonged erection, can be a side effect of trazodone. This case resolved spontaneously, with no lasting impact on sexual function.

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    Area of Science:

    • Pharmacology
    • Urology
    • Psychiatry

    Background:

    • Trazodone is an antidepressant medication.
    • Priapism is a medical emergency characterized by prolonged penile erection.
    • Antidepressant-induced priapism is a rare but serious adverse effect.

    Observation:

    • A case of priapism occurred in a patient treated with trazodone.
    • The erection resolved spontaneously within 4 hours.
    • The patient's subsequent sexual potency remained unimpaired.

    Findings:

    • This report details a case of priapism associated with trazodone.
    • No prior published reports linking antidepressants to priapism were found in the literature.
    • Eleven cases of priapism have been reported to trazodone manufacturers.

    Implications:

    • This case highlights a potential adverse effect of trazodone.
    • Healthcare providers should be aware of the risk of priapism with trazodone.
    • Further investigation into antidepressant-associated priapism may be warranted.

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